The Big Bang Theory

Set in Pasadena, California, the show is centered on five characters: two room mate geniuses who work at the California Institute of Technology, experimental physicist Leonard Hofstadter and theoretical physicist Sheldon Cooper; their neighbor across the hall Penny, a blonde waitress and aspiring actress; and Leonard and Sheldon's equally geeky and socially awkward co-workers and friends Howard Wolowitz, an aerospace engineer and a non-PhD from JPL, and Rajesh Koothrappali, an astrophysicist also working at Caltech.

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